HEDOCELL-1™

MESENCHYMAL STEM CELL (MSC) CONDITIONED MEDIA (CM)

Precision HA Microneedling Support | Single-Use | 6 mL Glass Vial

Professional Cosmetic Microneedling Kit

NOTE: A Cosmetic Microneedling Acknowledgment & Liability Waiver via DocuSign must be completed before shipping.

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A DIFFERENT STANDARD

HEDOCELL-1™ is a professional cosmetic microneedling system formulated in collaboration with Dr. William Gael, MD, a regenerative medicine physician with more than 20 years of experience in cellular therapies and extracellular signaling research.

The system is built around Wharton’s Jelly-derived Mesenchymal Stem Cell Conditioned Media and paired with Precision Hyaluronic Acid for controlled microneedling support.

Rather than combining multiple biological sources, HEDOCELL-1™ takes a focused, single-source approach designed around precision, controlled application and a simplified treatment environment.

WHARTON’S JELLY MSC CONDITIONED MEDIA | PRECISION HYALURONIC ACID | TWO-VIAL SYSTEM | CONTROLLED COSMETIC USE

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WHY HEDOCELL-1™ IS DIFFERENT

HEDOCELL-1™ is centered on one highly specific source:

WHARTON’S JELLY-DERIVED MSC CONDITIONED MEDIA

Conditioned media contains extracellular components released by cells into their surrounding culture environment.

HEDOCELL-1™ does not contain live stem cells.

The technology is centered on the conditioned media and its extracellular components, creating a focused cosmetic system designed to support the appearance and condition of skin following cosmetic microneedling.

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THE TWO-VIAL SYSTEM

VIAL 1 | HEDOCELL-1™

Mesenchymal Stem Cell (MSC) Conditioned Media (CM)

Wharton’s Jelly Source

VIAL 2 | PRECISION HYALURONIC ACID

Hyaluronic Acid, Aqua (Water), Phenoxyethanol

Precision HA provides hydration and controlled glide during microneedling.

HA FOR GLIDE. HEDOCELL-1™ AFTER TREATMENT.

This separation allows each component to perform a specific role within the protocol rather than combining everything into one formula.

This system is designed for topical cosmetic microneedling support only. It is not injectable.

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WHAT IT SUPPORTS

HEDOCELL-1™ is designed to support the appearance of:

SMOOTHER-LOOKING SKIN TEXTURE

MORE EVEN-LOOKING TONE

VISIBLE SKIN REFINEMENT

CALMER, BETTER-CONDITIONED SKIN

A SUPPORTED POST-MICRONEEDLING RECOVERY ENVIRONMENT

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THE HEDO MICRONEEDLING PROTOCOL

STEP 1 | PRECISION HA

GLIDE + CONTROL

Begin with clean, properly prepared skin.

Wear gloves and maintain strict sanitation throughout the treatment.

Apply a thin, even layer of Precision HA to the first treatment area.

Precision HA:

PROVIDES GLIDE FOR CONTROLLED NEEDLING

HELPS MAINTAIN HYDRATION

HELPS REDUCE DRAGGING ACROSS THE SKIN

Use a thin layer only. More product does not improve the treatment.

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STEP 2 | MICRONEEDLING

Work in small sections.

Use controlled, even passes.

Keep movement consistent and light.

Do not oversaturate the skin with product.

Recommended cosmetic depth: up to 0.5 mm

Depth should be adjusted according to experience, treatment area and skin tolerance.

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STEP 3 | HEDOCELL-1™

SIGNAL + SUPPORT

Once the section has been completed, apply HEDOCELL-1™ lightly over the treated area.

Do not flood the skin.

Gently press into the skin.

Do not aggressively massage.

Focus on an even, controlled application.

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STEP 4 | MOVE TO THE NEXT AREA

Repeat the same sequence:

PRECISION HA → MICRONEEDLE → HEDOCELL-1™

Working section by section provides greater control and consistency throughout the treatment.

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STEP 5 | FINAL APPLICATION

After completing the full treatment area, apply a light final layer of HEDOCELL-1™ and gently press into the skin.

Do not overapply.

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SIMPLE PROTOCOL

NEEDLE WITH PRECISION HA FOR GLIDE

APPLY HEDOCELL-1™ AFTER EACH COMPLETED AREA

GENTLY PRESS IN

FINISH WITH A LIGHT FINAL APPLICATION OF HEDOCELL-1™

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PROTOCOL GUIDELINES

Recommended cosmetic microneedling depth: up to 0.5 mm

Recommended cartridge: 24 needles or higher

Use sterile tools and maintain proper sanitation.

Do not combine with multiple boosters or strong active treatments.

Avoid use on compromised, infected or highly inflamed skin.

Do not use over active inflammatory acne lesions.

Not recommended for mesotherapy.

Not for injection.

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IMPORTANT SAFETY GUIDELINES

HEDOCELL-1™ is designed for controlled topical cosmetic use within a structured microneedling protocol.

Maintain strict sanitation throughout treatment.

Use only on clean, properly prepared skin.

Do not use on compromised, infected or highly inflamed skin.

Do not combine with aggressive active treatments during microneedling, including acids, retinoids or strong boosters.

Improper microneedling technique, excessive depth, repeated passes or inadequate sanitation can increase the risk of irritation, prolonged inflammation and infection.

If unusual or worsening redness, heat, swelling, pain or other concerning symptoms occur following treatment, discontinue use and seek appropriate medical evaluation.

HEDOCELL-1™ IS FOR TOPICAL COSMETIC USE ONLY.

DO NOT INJECT.

NOT INTENDED FOR MEDICAL USE.

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SINGLE-USE SYSTEM

HEDOCELL-1™ is designed as a single-use cosmetic treatment to help maintain product integrity and controlled handling.

Use sterile technique throughout the treatment and discard remaining product after completion according to the established HEDO protocol.

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THE HEDO STANDARD

CONTROLLED INPUTS OVER UNNECESSARY COMPLEXITY

SINGLE-SOURCE TECHNOLOGY OVER MIXED BIOLOGICAL BLENDS

PRECISION OVER OVERSTIMULATION

BARRIER SUPPORT AS AN ESSENTIAL PART OF THE RESULT

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WHAT YOU SEE IN THE SKIN

Skin that appears:

CALMER

SMOOTHER

MORE EVEN

MORE REFINED

BETTER CONDITIONED OVER TIME

Not overstimulated.

Not overworked.

Just treated with intention.

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RESERVED FOR ADVANCED HEDO PROTOCOLS

HEDOCELL-1™ is not a trend-driven formula.

It is a focused cosmetic microneedling system built around controlled application, single-source conditioned media and precision HA support.

In advanced skincare, purity and control matter.

Professional-grade skin renewal. Controlled cosmetic use.

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RETURNS & SAFETY NOTICE

Final Sale. This kit can be returned or exchanged only if it is unopened and unused, with its safety or tamper-evident seal intact where applicable.

If your order arrives damaged, defective or incorrect, we will provide a replacement or refund.

See the HEDO Return, Refund & Exchange Policy for complete details.

This policy helps protect product integrity, safety and quality for every client.