HEDOSOMES™

Lyophilized MSC-Derived Conditioned Media | Fresh Reconstitution Technology

Professional Cosmetic Reconstitution Kit

NOTE: A Cosmetic Microneedling Acknowledgment & Liability Waiver via DocuSign must be completed before shipping.

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A DIFFERENT STANDARD

HEDOSOMES™ is a professional two-vial cosmetic system featuring lyophilized MSC-derived conditioned media and 0.9% sterile saline diluent for fresh reconstitution immediately before use.

Developed in collaboration with Vince Liguori, a biotech executive and regenerative medicine advisor with extensive experience in biologics, stem cell product development and regulatory strategy, HEDOSOMES™ was created around a disciplined approach to sourcing, stabilization, preparation and controlled cosmetic use.

As CEO of Ageless Biotech, Vince's work has included next-generation biologic technologies, extracellular vesicle and stem cell-derived systems, biologic commercialization and clinical development strategy.

LYOPHILIZED MSC-DERIVED CONDITIONED MEDIA | TWO-VIAL SYSTEM | FRESH RECONSTITUTION | CONTROLLED COSMETIC USE

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HERE'S THE SCIENCE.

LYOPHILIZED MSC-DERIVED CONDITIONED MEDIA

MSC-derived conditioned media contains extracellular components released by mesenchymal stem cells into their surrounding culture environment.

HEDOSOMES™ does not contain live stem cells.

The technology is centered on MSC-derived conditioned media that has been lyophilized, or freeze-dried, prior to use.

This allows HEDOSOMES™ to remain in a dry format until the treatment is ready to begin.

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WHY LYOPHILIZATION?

Preserve First. Reconstitute When Ready.

Lyophilization removes water from the material through a controlled freeze-drying process, creating a dry format designed to support stability prior to reconstitution.

Instead of storing the conditioned media as a ready-to-use liquid, HEDOSOMES™ keeps the system lyophilized until the treatment is ready to begin.

Immediately before use, the powder is reconstituted with the supplied sterile saline.

This is not about managing degradation after the fact. It is about preserving integrity until the moment of use.

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THE TWO-VIAL SYSTEM

VIAL 1 | HEDOSOMES™

Lyophilized MSC-Derived Conditioned Media

VIAL 2 | STERILE SALINE DILUENT

0.9% Sterile Saline Diluent for Reconstitution

The two components remain separate until immediately before treatment.

LYOPHILIZED STORAGE → FRESH RECONSTITUTION → CONTROLLED TOPICAL APPLICATION

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WHY HEDO IS DIFFERENT

HEDO is not built around excess.

It is built around precision.

In a category where more ingredients can easily be mistaken for better technology, HEDO takes a more disciplined approach.

HEDOSOMES™ focuses on:

CONTROLLED INPUTS

LYOPHILIZED STABILITY

FRESH RECONSTITUTION

STRUCTURED APPLICATION

BARRIER-AWARE SUPPORT

NO UNNECESSARY FORMULA COMPLEXITY

The sophistication of a biologic-inspired cosmetic system isn't determined simply by the number of ingredients it contains.

How it is sourced, stabilized, prepared and used matters.

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FRESH RECONSTITUTION TECHNOLOGY

HEDOSOMES™ is supplied as a freeze-dried powder and reconstituted with the provided 0.9% sterile saline immediately before cosmetic use.

This provides a defined preparation point rather than maintaining the conditioned media indefinitely as a pre-mixed liquid.

Once reconstituted, the product is intended for prompt topical use according to the HEDO protocol.

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WHAT IT SUPPORTS

HEDOSOMES™ is designed to support the appearance of:

SMOOTHER-LOOKING SKIN

MORE REFINED TEXTURE

MORE EVEN-LOOKING TONE

CALMER, BETTER-CONDITIONED SKIN

MORE RESILIENT-LOOKING SKIN OVER TIME

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DIRECTIONS FOR RECONSTITUTION

Maintain strict sanitation throughout preparation.

STEP 1

Clean the vial stoppers thoroughly with alcohol before access.

STEP 2

Using a new sterile syringe and needle, withdraw the provided sterile saline and inject it into the HEDOSOMES™ vial.

STEP 3

Gently swirl until the lyophilized material is completely dissolved.

Do not shake.

STEP 4

Using a sterile syringe and needle, withdraw the reconstituted solution.

STEP 5

Remove and safely discard the needle before topical application.

STEP 6

Apply topically as part of the established HEDO cosmetic microneedling protocol.

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COSMETIC MICRONEEDLING PROTOCOL GUIDELINES

Recommended cosmetic depth: up to 0.5 mm

Recommended cartridge: 24 needles or higher

Maintain strict sanitation throughout preparation and treatment.

Use only on clean, properly prepared skin.

Avoid compromised, infected or highly inflamed skin.

Do not combine with strong acids, retinoids or aggressive boosters during treatment.

Not for mesotherapy.

Not for injection.

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SINGLE-USE COSMETIC FORMAT

HEDOSOMES™ is designed as a single-use cosmetic reconstitution system.

For optimal product integrity, reconstitute immediately before treatment and use promptly.

Discard any unused portion after the treatment and no later than 24 hours following reconstitution.

Follow the established product storage instructions.

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IMPORTANT SAFETY GUIDELINES

HEDOSOMES™ is designed for topical cosmetic use during superficial cosmetic microneedling protocols up to 0.5 mm.

It contains no live stem cells.

DO NOT INJECT.

NOT FOR MESOTHERAPY.

NOT INTENDED FOR MEDICAL USE.

NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE OR MEDICAL CONDITION.

Maintain strict sanitation throughout preparation and application.

Do not use on compromised, infected or highly inflamed skin.

Do not combine with aggressive active treatments during microneedling, including acids, retinoids or strong boosters.

Improper technique, poor sanitation or inappropriate product selection may increase the risk of irritation, prolonged inflammation or infection.

If unusual or worsening redness, heat, swelling, pain or other concerning symptoms occur, discontinue use and seek appropriate medical evaluation.

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THE HEDO STANDARD

CONTROLLED INPUTS OVER UNNECESSARY COMPLEXITY

SINGLE-SOURCE SIGNALING OVER MIXED BIOLOGICAL BLENDS

FRESH RECONSTITUTION OVER EXTENDED DEGRADATION WINDOWS

BARRIER SUPPORT AS AN ESSENTIAL PART OF THE RESULT

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WHAT YOU SEE IN THE SKIN

HEDOSOMES™ helps support skin that appears:

CALMER

SMOOTHER

MORE EVEN

MORE REFINED

MORE RESILIENT-LOOKING OVER TIME

Biologic-inspired skincare technologies continue to evolve.

What matters is not simply the name of the technology.

What matters is how it is sourced, stabilized, prepared and used.

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THE HEDO DIFFERENCE

HEDOSOMES™ is not a trend-driven formula.

It is a focused professional cosmetic system built around lyophilized MSC-derived conditioned media, fresh reconstitution and controlled topical application.

LYOPHILIZE. RECONSTITUTE. APPLY.

Precision at the moment of use.

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RESERVED FOR ADVANCED HEDO PROTOCOLS

Professional-Grade Skin Renewal | Controlled Cosmetic Use

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RETURNS & SAFETY NOTICE

Final Sale. This kit can be returned or exchanged only if it is unopened and unused, with its safety or tamper-evident seal intact where applicable.

If your order arrives damaged, defective or incorrect, we will provide a replacement or refund.

See the HEDO Return, Refund & Exchange Policy for complete details.

This policy helps protect product integrity, safety and quality for every client.